“HATE. LET ME TELL YOU HOW MUCH I'VE COME TO HATE YOU SINCE I BEGAN AS A HAEM REG. IF THE WORD HATE WAS ENGRAVED ON EACH NANO-ANGSTROM OF THE HUNDREDS OF MILLIONS OF CONSULT NOTES I HAVE WRITTEN IT WOULD NOT EQUAL ONE BILLIONTH OF THE HATE I FEEL FOR YOU ORDERING THROMBOPHILIA TESTING INAPPROPRIATELY.” Woah - Let’s calm down, that's a bit much. Cale and Bashar are exposed to Nick’s inner monologue as the Bloody Minded Crew learn about the what, when and when not of thrombophilia testing. 

TIMESTAMPS

0:52 - Nick gets stuck in an anger loop  
2:19 - Intro to thrombophilia testing  
4:25 - Inherited thrombophilias  
5:38 - Surprise historical diversion on antithrombin  
8:14 - Proteins C and S  
9:31 - Factor V Leiden  
10:56 - Prothrombin gene mutation  
11:52 - Risk profiles in inherited thrombophilia  
18:49 - Acquired thrombophilias  
18:56 - Antiphospholipid syndrome  
19:46 - PNH  
20:22 - JAK2  
21:08 - Mid-ep summary  
22:28 - The world's biggest soapbox: what not to do  
23:25 - Soapbox: no MTHFR pls  
25:19 - Soapbox: bad times to test  
26:46 - Soapbox: don't test the obvious provoked clots  
27:30 - Bonus soapbox: factor V levels vs Leiden  
28:54 - When SHOULD we test?  
30:41 - Benefits of testing  
32:33 - Clinical scenario: spoiler, no real answer  
33:26 - Scenarios where you might test  
37:49 - Take home messages  

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